Topic 8 Flipped Video Playlist Link
http://bit.ly/TylerTopic8Metabolism
http://bit.ly/TylerTopic8CellularRespiration
http://bit.ly/TylerTopic8Photosynthesis
Leaf Disc Lab Prep Video Bozeman Science - https://www.youtube.com/watch?v=ZnY9_wMZZWI
https://biomanbio.com/HTML5GamesandLabs/PhotoRespgames/photointeractivehtml5page.html
http://bit.ly/TylerTopic8CellularRespiration
http://bit.ly/TylerTopic8Photosynthesis
Leaf Disc Lab Prep Video Bozeman Science - https://www.youtube.com/watch?v=ZnY9_wMZZWI
https://biomanbio.com/HTML5GamesandLabs/PhotoRespgames/photointeractivehtml5page.html
Video Due Dates:
Check Planbook under Class Info Tab. It is hyperlinked at the top. I will edit the due dates here soon!
Metabolism/Enzymes AND Enzyme Inhibition Part 1 -
Using Inhibitors in Drug Design -
Glycolysis Parts 1 and 2 -
Link Reaction/ Krebs Cycle AND Electron Transport -
Cellular Respiration Summary and Key Points -
Intro to Photosynthesis -
Light Dependent Reactions Parts 1 and 2 will be watched in class
Cyclic vs Noncyclic Photophosphorylation -
The Calvin Cycle video will be watched in class
Elucidating the Calvin Cycle AND Photosynthesis Summary -
Check Planbook under Class Info Tab. It is hyperlinked at the top. I will edit the due dates here soon!
Metabolism/Enzymes AND Enzyme Inhibition Part 1 -
Using Inhibitors in Drug Design -
Glycolysis Parts 1 and 2 -
Link Reaction/ Krebs Cycle AND Electron Transport -
Cellular Respiration Summary and Key Points -
Intro to Photosynthesis -
Light Dependent Reactions Parts 1 and 2 will be watched in class
Cyclic vs Noncyclic Photophosphorylation -
The Calvin Cycle video will be watched in class
Elucidating the Calvin Cycle AND Photosynthesis Summary -
PowerPoints Topic 8 AHLPresentation 1: Metabolism (Enzymes)
Presentation 2: Cellular Respiration Presentation 3: Photosynthesis |
Notes Packets Topic 8 AHL
|
Other Flipped Videos
Bozeman Science Cellular Respiration and Photosynthesis Videos
http://www.bozemanscience.com/013-photosynthesis-and-respiration
Dan Rott Flipped Videos:
SL Enzymes
https://www.youtube.com/watch?v=9koQPHeeQW4
Topic 8.1
https://www.youtube.com/watch?v=OLHvzg8JV-8
Cellular Respiration
Part 1 – https://www.youtube.com/watch?v=SIZnLjfpyBY
Part 2 - https://www.youtube.com/watch?v=n7cmPvDkQ7g
Photosynthesis
Part 1 - https://www.youtube.com/watch?v=LxyxvAyizAI
Part 2 - https://www.youtube.com/watch?v=Xk18OnnaOmY
Part 3 - https://www.youtube.com/watch?v=xpwF9ZYaVVM
Other Useful Videos to Search:
Ted-Ed
Amoeba Sisters
Crash Course
http://www.bozemanscience.com/013-photosynthesis-and-respiration
Dan Rott Flipped Videos:
SL Enzymes
https://www.youtube.com/watch?v=9koQPHeeQW4
Topic 8.1
https://www.youtube.com/watch?v=OLHvzg8JV-8
Cellular Respiration
Part 1 – https://www.youtube.com/watch?v=SIZnLjfpyBY
Part 2 - https://www.youtube.com/watch?v=n7cmPvDkQ7g
Photosynthesis
Part 1 - https://www.youtube.com/watch?v=LxyxvAyizAI
Part 2 - https://www.youtube.com/watch?v=Xk18OnnaOmY
Part 3 - https://www.youtube.com/watch?v=xpwF9ZYaVVM
Other Useful Videos to Search:
Ted-Ed
Amoeba Sisters
Crash Course
Useful Links
Virtual Lab - Enzymes
http://www.mhhe.com/biosci/genbio/virtual_labs/BL_11/BL_11.html
http://www.ucl.ac.uk/~ucbcdab/enzass/enzymass.htm
Enzymes - what are they and how do they work
What is an enzyme? is a great place to start by Northland Community College
How enzymes work by Biotopics
How enzymes work by McGraw and Hill
Activation energy and the stressing of bonds explained by St Olaf College
Enzyme action and the hydrolysis of sucrose by McGraw and Hill
Inhibition and Metabolic Pathways
Allosteric (non-competitive) inhibition by St Olaf College
Example of a biochemical pathway by St Olaf College
Feedback (end product) inhibition from McGraw Hill
Example metabolic pathway, from McGraw Hill
Enzyme inhibition from Wiley Interscience
Cell Respiration
Cellular respiration by PH School
Cellular respiration by Sunamas Inc.
Cellular respiration a 3D animation by McGraw and Hill
Cellular respiration by Handwritten tutorials (below)
Glycolysis
Glycolysis by Smith University
How glycolysis works by McGraw and Hill
Glycolysis and fermentation in yeast by Indiana Uni has more detail than needed, but nicely illustrates that glycolysis is a metabolic pathway
Glycolysis by IUBMB again contains more detail than needed, but does neatly show the bond breaking and forming
Glycolysis by John Kyrk contains more detail than needed, but is a nice animation
Glycolysis by Cornell University
Glycolysis by National Louis University
Krebs cycle
Citric acid cycle by National Louis University
The citric acid cycle by Wiley
The citric acid cycle by Interactive concepts in biochemistry
How the Krebs cycle works by McGraw and Hill
Krebs cycle by John Kyrk contains more detail than needed, but is a nice animation
Oxidative Phosphorylation
Electron transport and chemiosmosis by National Louis University
Oxidative Phosphorylation by Interactive concepts in biochemistry
Oxidative phosphorylation by Purdue University
Electron transport system and ATP synthesis by McGraw and Hill
Mitochondria/electron transport by John Kyrk contains more detail than needed, but is a nice animation
Chloroplast structure
The busy leaf by FTExploring is a good introduction and nicely links structure of the leaf to function
Photosynthesis (overview)
Photosynthesis by the University of Illinois (lecture notes and nice diagrams)
Photosynthesis by Interactive concepts in biochemistry
Photosynthesis by National Louis University (lecture notes)
Photosynthesis by McGraw and Hill (great narrated animation)
Light Dependent reactions
Harvesting light by Sunamas Inc.
An animation of the light dependent reactions by Mr Brown (not annotated - possible student activity)
Light reactions in photosynthesis by Smith University
Light reactions by John Kyrk
Photosynthesis - light dependent reactions by St Olaf College
Visualisation of Photosynthesis from NDVirtualCell
Photosynthesis: light reactions by Khan Academy
Photosynthesis: light reactions and photophosphorylation by Khan Academy
Photosynthesis electron transport and ATP synthesis by McGraw and Hill (relates cell structures to function)
Light Independent reactions
Carbon fixation in photosynthesis by Smith University
Biosynthetic reactions by John Kyrk
Photosynthesis: Calvin cycle by Khan Academy
Calvin cycle by McGraw and Hill
Nature's smallest factory: the Calvin cycle by TED ed
http://www.mhhe.com/biosci/genbio/virtual_labs/BL_11/BL_11.html
http://www.ucl.ac.uk/~ucbcdab/enzass/enzymass.htm
Enzymes - what are they and how do they work
What is an enzyme? is a great place to start by Northland Community College
How enzymes work by Biotopics
How enzymes work by McGraw and Hill
Activation energy and the stressing of bonds explained by St Olaf College
Enzyme action and the hydrolysis of sucrose by McGraw and Hill
Inhibition and Metabolic Pathways
Allosteric (non-competitive) inhibition by St Olaf College
Example of a biochemical pathway by St Olaf College
Feedback (end product) inhibition from McGraw Hill
Example metabolic pathway, from McGraw Hill
Enzyme inhibition from Wiley Interscience
Cell Respiration
Cellular respiration by PH School
Cellular respiration by Sunamas Inc.
Cellular respiration a 3D animation by McGraw and Hill
Cellular respiration by Handwritten tutorials (below)
Glycolysis
Glycolysis by Smith University
How glycolysis works by McGraw and Hill
Glycolysis and fermentation in yeast by Indiana Uni has more detail than needed, but nicely illustrates that glycolysis is a metabolic pathway
Glycolysis by IUBMB again contains more detail than needed, but does neatly show the bond breaking and forming
Glycolysis by John Kyrk contains more detail than needed, but is a nice animation
Glycolysis by Cornell University
Glycolysis by National Louis University
Krebs cycle
Citric acid cycle by National Louis University
The citric acid cycle by Wiley
The citric acid cycle by Interactive concepts in biochemistry
How the Krebs cycle works by McGraw and Hill
Krebs cycle by John Kyrk contains more detail than needed, but is a nice animation
Oxidative Phosphorylation
Electron transport and chemiosmosis by National Louis University
Oxidative Phosphorylation by Interactive concepts in biochemistry
Oxidative phosphorylation by Purdue University
Electron transport system and ATP synthesis by McGraw and Hill
Mitochondria/electron transport by John Kyrk contains more detail than needed, but is a nice animation
Chloroplast structure
The busy leaf by FTExploring is a good introduction and nicely links structure of the leaf to function
Photosynthesis (overview)
Photosynthesis by the University of Illinois (lecture notes and nice diagrams)
Photosynthesis by Interactive concepts in biochemistry
Photosynthesis by National Louis University (lecture notes)
Photosynthesis by McGraw and Hill (great narrated animation)
Light Dependent reactions
Harvesting light by Sunamas Inc.
An animation of the light dependent reactions by Mr Brown (not annotated - possible student activity)
Light reactions in photosynthesis by Smith University
Light reactions by John Kyrk
Photosynthesis - light dependent reactions by St Olaf College
Visualisation of Photosynthesis from NDVirtualCell
Photosynthesis: light reactions by Khan Academy
Photosynthesis: light reactions and photophosphorylation by Khan Academy
Photosynthesis electron transport and ATP synthesis by McGraw and Hill (relates cell structures to function)
Light Independent reactions
Carbon fixation in photosynthesis by Smith University
Biosynthetic reactions by John Kyrk
Photosynthesis: Calvin cycle by Khan Academy
Calvin cycle by McGraw and Hill
Nature's smallest factory: the Calvin cycle by TED ed
8.1 Metabolism
Nature of science:
Developments in scientific research follow improvements in computing—developments in bioinformatics, such as the interrogation of databases, have facilitated research into metabolic pathways. (3.8)
Understandings:
Applications and skills:
Guidance:
Theory of knowledge:
Utilization:
Aims:
8.2 Cell Respiration
Essential idea: Energy is converted to a usable form in cell respiration.
Nature of science:
Paradigm shift—the chemiosmotic theory led to a paradigm shift in the field of bioenergetics. (2.3)
Understandings:
Applications and skills:
Guidance:
Theory of knowledge:
8.3 Photosynthesis
Essential idea: Light energy is converted into chemical energy.
Nature of science:
Developments in scientific research follow improvements in apparatus—sources of 14C and autoradiography enabled Calvin to elucidate the pathways of carbon fixation. (1.8)
Understandings:
Applications and skills:
Theory of knowledge:
Utilization:
Aims:
Nature of science:
Developments in scientific research follow improvements in computing—developments in bioinformatics, such as the interrogation of databases, have facilitated research into metabolic pathways. (3.8)
Understandings:
- Metabolic pathways consist of chains and cycles of enzyme-catalysed reactions.
- Enzymes lower the activation energy of the chemical reactions that they catalyse.
- Enzyme inhibitors can be competitive or non-competitive.
- Metabolic pathways can be controlled by end-product inhibition.
Applications and skills:
- Application: End-product inhibition of the pathway that converts threonine to isoleucine.
- Application: Use of databases to identify potential new anti-malarial drugs.
- Skill: Calculating and plotting rates of reaction from raw experimental results.
- Skill: Distinguishing different types of inhibition from graphs at specified substrate concentration.
Guidance:
- Enzyme inhibition should be studied using one specific example for competitive and non-competitive inhibition.
Theory of knowledge:
- Many metabolic pathways have been described following a series of carefully controlled and repeated experiments. To what degree can looking at component parts give us knowledge of the whole?
Utilization:
- Many enzyme inhibitors have been used in medicine. For example ethanol has been used to act as a competitive inhibitor for antifreeze poisoning.
- Fomepizole, which is an inhibitor of alcohol dehydrogenase, has also been used for antifreeze poisoning.
Aims:
- Aim 6: Experiments on enzyme inhibition can be performed.
- Aim 7: Computer simulations on enzyme action including metabolic inhibition are available.
8.2 Cell Respiration
Essential idea: Energy is converted to a usable form in cell respiration.
Nature of science:
Paradigm shift—the chemiosmotic theory led to a paradigm shift in the field of bioenergetics. (2.3)
Understandings:
- Cell respiration involves the oxidation and reduction of electron carriers.
- Phosphorylation of molecules makes them less stable.
- In glycolysis, glucose is converted to pyruvate in the cytoplasm.
- Glycolysis gives a small net gain of ATP without the use of oxygen.
- In aerobic cell respiration pyruvate is decarboxylated and oxidized, and converted into acetyl compound and attached to coenzyme A to form acetyl coenzyme A in the link reaction.
- In the Krebs cycle, the oxidation of acetyl groups is coupled to the reduction of hydrogen carriers, liberating carbon dioxide.
- Energy released by oxidation reactions is carried to the cristae of the mitochondria by reduced NAD and FAD.
- Transfer of electrons between carriers in the electron transport chain in the membrane of the cristae is coupled to proton pumping.
- Oxygen is the final electron acceptor.
- In chemiosmosis protons diffuse through ATP synthase to generate ATP.
- Oxygen is needed to bind with the free protons to maintain the hydrogen gradient, resulting in the formation of water.
- The structure of the mitochondrion is adapted to the function it performs.
Applications and skills:
- Application: Electron tomography used to produce images of active mitochondria.
- Skill: Analysis of diagrams of the pathways of aerobic respiration to deduce where decarboxylation and oxidation reactions occur.
- Skill: Annotation of a diagram of a mitochondrion to indicate the adaptations to its function.
Guidance:
- The names of the intermediate compounds in gylcolysis and the Krebs cycle are not required.
Theory of knowledge:
- Peter Mitchell’s chemiosmotic theory encountered years of opposition before it was finally accepted. For what reasons does falsification not always result in an immediate acceptance of new theories or a paradigm shift?
8.3 Photosynthesis
Essential idea: Light energy is converted into chemical energy.
Nature of science:
Developments in scientific research follow improvements in apparatus—sources of 14C and autoradiography enabled Calvin to elucidate the pathways of carbon fixation. (1.8)
Understandings:
- Light-dependent reactions take place in the thylakoid membranes and the space inside them.
- Light-independent reactions take place in the stroma.
- Reduced NADP and ATP are produced in the light-dependent reactions.
- Absorption of light by photosystems generates excited electrons.
- Photolysis of water generates electrons for use in the light-dependent reactions.
- Transfer of excited electrons occurs between carriers in thylakoid membranes.
- Excited electrons from Photosystem II are used to contribute to generate a proton gradient.
- ATP synthase in thylakoids generates ATP using the proton gradient.
- Excited electrons from Photosystem I are used to reduce NADP.
- In the light-independent reactions a carboxylase catalyses the carboxylation of ribulose bisphosphate.
- Glycerate 3-phosphate is reduced to triose phosphate using reduced NADP and ATP.
- Triose phosphate is used to regenerate RuBP and produce carbohydrates.
- Ribulose bisphosphate is reformed using ATP.
- The structure of the chloroplast is adapted to its function in photosynthesis.
Applications and skills:
- Application: Calvin’s experiment to elucidate the carboxylation of RuBP.
- Skill: Annotation of a diagram to indicate the adaptations of a chloroplast to its function.
Theory of knowledge:
- The lollipop experiment used to work out the biochemical details of the Calvin cycle shows considerable creativity. To what extent is the creation of an elegant protocol similar to the creation of a work of art?
Utilization:
- The Global Artificial Photosynthesis (GAP) project aims to create an artificial “leaf” within the next decade. An electronic version of the leaf that creates oxygen and hydrogen from water and sunlight has already been invented and will be developed for use in the next decade.
Aims:
- Aim 6: Hill´s method demonstrating electron transfer in chloroplasts by observing DCPIP reduction, immobilization of a culture of an alga such as Scenedesmus in alginate beads and measurement of the rate of photosynthesis by monitoring their effect on hydrogencarbonate indicator are all possible experiments.